Calendar

Feb
28
Thu
Webinar: Seperating effects of the treatment from the underlying disease
Feb 28 @ 9:00 AM – 10:00 AM

Please check our dedicated “Hot Topic Webinar”-site for much more information…

Mar
15
Fri
Early bird Deadline: Pharmacoepi Summer School June, Grenaa
Mar 15 all-day

Course descriptions, prices, and registration at http://kea.au.dk/education/summer-school/

Mar
22
Fri
Dr. Med.Sci dissertation defence by Henrik Støvring: Using prescription data as indicators of disease or drug use, new analytic methods based on renewal processes @ Lille Anatomisk Auditorium, Aarhus University
Mar 22 @ 2:00 PM

Henrik Støvring,
Department of Public Health Aarhus University will defend his Dr.Med.Sci. dissertation titled

Using prescription data as indicators of disease or drug use, new analytic methods based on renewal processes

on Friday, 22 March 2019 at 14:00 at Aarhus University in Lille Anatomisk Auditorium (building 1231, room 424), Wilhelm Meyers Alle 3, DK-8000 Aarhus C.

Opponents:
Associate Professor Fredrik Granath, Clinical Epidemiology Division, Dept. Medicine Solna, Karolinska Institutet

Professor Robert J Glynn, Division of Pharmacoepidemiology & Pharmacoeconomics, Harvard Medical School

Professor Lars Pedersen (chairperson), Klinisk Epidemiologisk Afdeling, Aarhus University

The dissertation can be acquired by contacting Henrik Støvring (stovring@ph.au.dk).

Abstract
Electronic prescription registries are the fundamental data sources in modern pharmacoepidemiology. Information on the single prescriptions of each patient is detailed, but the duration of the prescription is often not known, i.e. it is not recorded how long a patient remains treated after the redemption. The first part of the dissertation shows how it is possible to study the epidemiology of diabetes in Denmark using only information on redeemed prescriptions. The studies develop a book-keeping approach in which the number of treated patients (prevalence) at the end of the year is given by the prevalence at the beginning of the year plus the number of patients initiating treatment during the year (incidence) minus the number of patients stopping treatment during the year (stopping).

Stopping is further subdivided into treatment cessation and death. The two studies in this part use a simple classification to determine who are considered treated at the beginning of the year based on whether the patient had redeemed a prescription in the preceding year or not. The studies showed that changes in diabetes incidence had little effect on the contemporary change in diabetes prevalence in the period 1992-2003 in Funen County, Denmark. The second part consists of six studies that develop and apply new statistical methods to estimate prevalence, incidence, stopping of treatment, prescription durations and the probability of an individual being treated on a given day. Existing methods in pharmacoepidemiology are largely based on decision rules for determining treatment status at a given point in time, and so are not based on a statistical model as such. The Waiting Time Distribution (WTD) is the distribution of time from the beginning of a time window until the first prescription redemption of each patient within the window. The WTD was first suggested as a tool for graphical analysis without an underlying formal statistical model. This part of the dissertation shows how the WTD approach can be formalized using theory on renewal processes, which allows establishing a parametric model for likelihood analysis. The model is developed for both closed and open cohorts, for the first 2 redemption in a time window (ordinary WTD) and the last redemption (reverse WTD), and for inclusion of covariates. Properties of the models are studied both in simulation studies as well as in pharmacoepidemiological applications. The theoretical foundation provided by formulating a likelihood-based model allows for further development of new statistical approaches in pharmacoepidemiology.

Mar
27
Wed
Webinar: Diclofenac and cardiovascular risks
Mar 27 @ 9:00 AM – 10:00 AM
Apr
25
Thu
Webinar: New-user active comparator cohort studies
Apr 25 @ 9:00 AM – 10:00 AM

Please check our dedicated “Hot Topic Webinar”-site for much more information…

May
24
Fri
Temadag: EU’s persondataforordning for dummies part 2 @ Winsløw parken
May 24 @ 9:30 AM – 2:30 PM

Til alle interesserede,

Dansk Selskab for Farmakoepidemiologi (DSFE) og Dansk Selskab for Epidemiologi (DES) afholder fredag d. 24. maj 2019 en temadag ’EUs Persondataforordning for dummies – part 2’
i Odense.

Temadagen er en efterfølger til den populære temadag i maj 2018 omhandlende samme emne. Konklusionen efter sidste temadag var at ansvaret er blevet decentraliseret og nu ligger hos de enkelte forskere. Dagen vil følge op på, hvordan vi står stillet et år efter persondatafordningens ikrafttrædelse og give et overblik over de gældende juridiske rammer for brug af sundhedsdata. Deltag og få svar på spørgsmål som: Hvilke tilladelser/dokumentation skal jeg have på plads inden jeg søger om data? Hvordan bruger jeg sundhedsdata i overensstemmelse med den nye lovgivning? Hvordan skriver jeg en god projekt- og udtræksbeskrivelse til Sundhedsdatastyrelsen eller Danmarks statistik?

Vi sender det endelige program ud inden længe, men hvis ovenstående lyder relevant for dig, så tilmeld dig eller reservér dagen allerede nu. Der vil også være mulighed for at følge dagen online, hvis du er forhindret i at komme til Odense.

Fakta om temadagen
Tidspunkt: Fredag d. 24. maj 2019 kl. 10-14 (kaffe fra 9.30)
Sted: Syddansk Universitet, Winsløwsparken 17, lokale 17.109 (1. sal)
Forplejning: Formiddagskaffe og frokost (kræver tilmelding)
Pris: Gratis for alle
Antal pladser: 75 pladser + webadgang
Tilmelding per mail: info@dsfe.dk senest d. 16. maj 2018. Angiv gerne om du ønsker frokost og om du deltager fysisk eller online

Jun
17
Mon
Pharmacoepi Summer School @ Grenaa, Denmark
Jun 17 – Jun 21 all-day

Day 1 and 2:  Advanced topics in pharmacoepidemiology   – Prof. Alan Brookhart University of North Carolina at Chapel Hill
Day 3:  Self-controlled study designs   – Prof. Ian Douglas London School of Hygiene and Tropical Medicine
Day 4: Perinatal and reproductive pharmacoepidemiology    – Prof. Vera Ehrenstein Aarhus University & Prof. Irene Petersen University College London
Day 5 (half day): Reporting our research using routinely-collected health data better – Introducing STROBE, RECORD, and RECORD-PE   – Prof. Sinead Langan London School of Hygiene and Tropical Medicine

Course descriptions, prices, and registration at  http://kea.au.dk/education/summer-school/

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